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Find out if BETASERON (Interferon Beta-1b) is the best option for you

WHAT EXACTLY IS BETASERON?

This drug is a type of protein (Interferon beta-1b) that occurs naturally in the human body. It was the first treatment for Relapsing and Remitting forms of Multiple Sclerosis (RRMS) approved by the Food and Drug Administration (FDA).



This particular drug gives you the highest dose of all the interferons (250 mcg) given every other day via subcutaneous injections.

Studies have shown that long term use of this drug after the first event – attack - may reduce the risk of a second MS attack by 50%.

Several studies also indicate that it can be used indefinitely. It has a comparable safety record to other interferon-based drugs, which are considered safe for long-term use as long as appropriate monitoring for liver function and blood cell count are maintained.

THE HISTORY

Betaseron is manufactured by the pharmaceutical corporation Bayer and it became available for the treatment of Relapsing Remitting MS (RRMS) in 1993.


SOME NECESSARY PRECAUTIONS YOU NEED TO REMEMBER WHEN TAKING THIS MEDICINE

You need to do blood tests every three months during the first year to check white blood cell count and liver function. After 12 months, blood work can be reduced to once every four months.


WHAT ARE PATIENTS SAYING ABOUT THIS TREATMENT OPTION?

The needle is 0.5 inches long, and is 27gauge which makes it a pretty thin needle to use with the automatic injecting device provided with the medication called Betaject 3

This MS treatment option is the interferon with the longest record of clinical evidence and has been shown to be safe in people using it for over 17 continuous years.


THE MOST FREQUENT SIDE EFFECTS ARE :

The side effects of this medication are similar to those of other interferon-based therapies.

  1. Flu-Like Symptoms: Are the most common side effect of this drug. Around 76% of patients experienced them. These symptoms include: fever, chills, sweating, muscle aches and fatigue. They can last for 24 to 36 hours. They are usually worst after the first injection and gradually lessens with each injection, so that most people do experience it (or it is tolerable) after six months.

    These particular side effects can be reduced by starting with a low dose and increasing to a full dose gradually, over several weeks. It is highly recommended taking ibuprofen or acetaminophen a couple hours before and after to help you with some of these side effects.

  2. Red spots: Around 85% of all MSers using Betaseron complain of this side effect occurring at the site of injections. It may last several weeks. These can break down into sores (injection-site necrosis) in 4% of cases.

  3. Problems causing liver damage: Hepatitis and elevated levels of liver enzymes, which can cause liver damage, have been reported. Regular monitoring is required to prevent liver damage from occurring or progressing.

  4. Blood Counts: This medication can cause a decrease in the numbers of red and white blood cells, as well as a reduction in the number of platelets in the blood.

  5. Depression: This drug should be used with caution in patients with depression.

OTHER IMPORTANT INFORMATION YOU SHOULD KNOW

Contraindications/Precautions: Not contraindicated for use with any drug, including high dose steroids (Solu-Medrol). People with a history of depression should be monitored closely while using it. During clinical trials, there were five suicide attempts (one successful) among people taking Betaseron. Treatment with Betaseron is not advised for those patients suffering from blood problems such as anemia.

PREGNANCY:

This drug has a pregnancy category C, which means that it caused some harm to fetuses in animal studies, but the effect in humans is unknown. It should not be used by women who are pregnant and should be stopped before trying to conceive for some time (usually one to three months) - discuss this with your doctor. This medication should not be used by women who are breastfeeding.

YOUR DRUG COST:

The cost of this medication is between US $22,000 and US $33,000 a year. (You can check exact prices at DestinationRx.com

Betaseron is covered by most private insurance plans. Additionally, Bayer HealthCare Pharmaceuticals operates the Betaseron Patient Assistance Program to help patients who, after pursuing other forms of coverage and assistance, cannot otherwise afford the drug. You can call (877) 836-5724 for more information or contact MSPathways.com for help

Your doctor's office or your local chapter of the The National MS Society should also be able to assist you in determining financial options for affordable treatment.



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